This is a brilliant post from CrossFit San Francisco’s Kelly Starett on the use of NSAIDs following workouts. It demonstrates exactly what I deeply admire about CrossFit’s most brilliant minds. No matter how easy something makes life, long term health and wellness IS NEVER WORTH SACRIFICING!! Read on…
“Ok. Ibuprofen has no place in the life of the athlete obsessed with chasing performance. Taking an anti-inflammatory drug of any kind makes tendons and ligaments weaker, and stops muscles from getting stronger. Is this clear enough? Yes, we used to call it Vitamin I. Yes, we used to say that RICE should have a second “I” in it (Rest, Ice, Ibuprofen, Compression, Elevation).
We used to also do “21’s” on back and bi’s day too. It’s not ok.
Here’s the low down. Ibuprofen is an NSAID (Non-Steroidal-Anti-Inflammatory-Drug) which is believed to work through the inhibition of cyclooxygenase (COX), thus inhibiting prostaglandin synthesis. Prostaglandins, are like hormones in that they act as chemical messengers, but do not move to other sites, but work right within the cells where they are synthesized. Prostaglandins are vital mediators of the inflammatory cascade. The swelling and subsequent prostaglandin production signals all of the important cells circulating in your body to come and fix/reinforce the challenged tissues. That’s right, all that soreness you feel after Fran is the resultant swelling from all the micro-damage you’ve done to your muscles. It’s this very inflammatory response that is responsible for making you a BETTER ATHLETE. The Worst thing you can do is to go through a horrible workout like Fran and then not reap the resultant gains from the training stimulus.
No good coach should allow their athletes to take ibuprofen at anytime. Even if they are hung over..
Why?
NSAIDs have been shown to delay and hamper the healing in all the soft tissues, including muscles, ligaments, tendons, and cartilage. Anti-inflammatories can delay healing and delay it significantly, even in muscles with their tremendous blood supply. In one study on muscle strains, Piroxicam (an NSAID) essentially wiped out the entire inflammatory proliferative phase of healing (days 0-4). At day two there were essentially no macrophages (cells that clean up the area) in the area and by day four after the muscle strain, there was very little muscle regeneration compared to the normal healing process. (Greene, J. Cost-conscious prescribing of nonsteroidal anti-inflammatory drugs for adults with arthritis. Archives of Internal Medicine. 1992; 152:1995-2002.)
Long term NSAID use is hard on your tissues and directly responsible from some pretty gnarly chronic body issues.
So how do we treat acute inflammatory/inflammation pain?
You know the answer.
Ice. (Maybe a little Tylenol if you really, really need it, it’s not an NSAID after all)
But remember, Acetaminophen causes three times as many cases of liver failure as all other drugs combined and is the most common cause of acute liver failure in the United States. Even recommended doses especially combined with even small amounts of alcohol (Yes you Crossfitters) have caused irreversible liver failure. Don’t be so cavalier about treating your muscle soreness with drugs. Taking pain meds of any kind is serious.
Can you see the difference between treating pain and treating inflammation? Control swelling and Pain with Ice as seen below, it won’t short circuit the way your body actually heals itself and becomes stronger. (Hell, the Ice bath might make you a little stronger too.)
Bask in your soreness!Brag about it at work as your friends help you get up off the toilet. And above all, practice all the recovery tricks you know! These include: Proper nutrition, fluid intake, ice bath, fish oil, active recovery, stretching, massage, etc.
Hell, you can even sneak in another quick workout the next day before the 48 hour soreness beat down really kicks in! Quick, let’s do Fight Gone Bad before you get too sore from yesterday’s double fran! For example.
Seriously. Knock it off. Get off the Vitamin I.

i saw this yesterday and immediately went, “oh. damn.” i have often nonchalantly thrown back advil when particularly sore. fortunately i have moved to ice cups and constrast showers the last few months i’m definitely going to stay there! great post!
I hate any meds. I love the soreness! an ice bath followed by a hot shower, some self massage and maybe some biofreeze if needed.
uhhhhhhhhm, I just took 800mgs……tight lower back from deadlifting. I just wanted to throw it out there that I am digging the strength bias followed by a met – con!! Mike had mentioned that there is concern that women don’t like the olympic lifting aspect of crossfit. NOT true here. I love it.
Brenda it was uper fun lifting with you!!!!!!!! You crushed the deadlift…. AWE-some work. Sara I heard you DEMOLISHED this lift. I am in awe! I missed the shoulder press and want to fit it in somehow. Trying to get it done at home is a bust for me… I need the peer pressure.
I also wanted to mention that I am going to Yoga Oasis for hour yoga ($4) classes. Everything about it compliments crossfit. More flexibility + wrist/forearm/ankle work = a more well rounded crossfitter. These classes are done to music from Led Zepplin – Krishna Das. Check it out!!
Oh crap! I’ve been downing the ibuprofen to chase the inflamation away for a while now. I guess I’ll quadruple up on the ice treatments and maybe more rest… My liver thanks you, Jen.
Awesome article, Jen. I highly recommend the homeopathic ointment Traumeel for muscle soreness or injury pain. A friend suggested it to me when I injured my back in San Diego last month. It was a lifesaver!
I am always leery of taking any pain meds cause I’m affraid of hurting myself when I can’t feel as much. I knew that Tylenol had alot of other draw backs but I had no idea Advil was so bad. Thanks. The more I hear from you guys the gladder I am that you are in my life. I feel so great these days. I can’t wait to feel and see how I am a year from now.
E
How does one take a ice bath? Do you buy 20 lbs of ice throw it in a tub and jump in? How do you know you need to take an ice bath?